Prevalence, risk factors and survival of lung cancer in the idiopathic pulmonary fibrosis

Kyung Jong LeeMan Pyo ChungYoung Whan KimJae Ho LeeKyu-Sik KimJeong Seon RyuHong Lyeol LeeSung Woo ParkChoon Sik ParkSoo-Tak UhYong Chul LeeSeoung Ju ParkKwan Hyoung KimYoung June JeonWon Il ChoiYong Bum ParkDong Soon KimSung Hwan JeongJin Hwa LeeMoo Suk Park
Dept. of Internal Medicine (내과학)
Issue Date
Thorcic Cancer, Vol.3(2) : 150-155, 2012
Background: The aim of this study was to evaluate the prevalence, risk factors, and survival of lung cancer in patients with idiopathic pulmonary fibrosis (IPF). Methods: IPF with lung cancer from tertiary hospitals consisted of 1685 patients who had been diagnosed between 2003 and 2007. We reviewed their medical records retrospectively to evaluate the prevalence, risk factors and prognosis of lung cancer in IPF patients. Results: Among all patients with IPF, 114 cases (6.8%) had lung cancer with IPF. The incidence of lung cancer in patients with IPF was 1.03 persons per 100 person-year (25 patients/2408 years). Most cases of lung cancer (73/114, 68.9%) were located in IPF-associated areas; the lung cancer typically developed in periph- eral and lower lobe areas. The study revealed that forced vital capacity (% predicted) at the initial diagnosis and development of lung cancer were independent prognostic factors in patients with IPF. Conclusions: Lung cancer in patients with IPF was significantly related with the IPF prognosis. An active evaluation should be performed in patients with IPF to detect lung cancer early. Keywords idiopathic pulmonary fibrosis; lung cancer; prevalence.
idiopathic pulmonary fibrosislung cancerprevalence
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1. Journal Papers (연구논문) > 1. School of Medicine (의과대학) > Dept. of Internal Medicine (내과학)
Keimyung Author(s)
전영준; 최원일
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