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Comparison of Peritoneal Dialysis and Hemodialysis After Kidney Transplant Failure

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Affiliated Author(s)
황은아박성배한승엽
Alternative Author(s)
Hwang, Eun AhPark, Sung BaeHan, Seung Yeup
Journal Title
Transplantation Proceedings
ISSN
0041-1345
Issued Date
2013
Abstract
Background. Patients with a failed kidney transplant represent a unique chronic kidney
disease population that is increasing in number and is at high risk of morbidity and
mortality. Among transplant-naïve patients, those treated with peritoneal dialysis (PD)
show an early survival advantage compared with those treated with hemodialysis (HD). But
any advantage of PD after allograft failure is unknown. The aim of this study was to
investigate the clinical outcomes of patients with failed allografts according to the type of
dialysis modality.
Method. We reviewed medical records of patients who initiated dialysis after kidney
transplant failure from November 1982 to May 2011. Demographics features, clinical data,
and survival outcomes were compared between PD and HD patients who had experienced
allograft failure.
Results. The 182 patients with failed allografts showed the most common cause to be
chronic rejection. The median duration of function before allograft failure was 74.0
months. After allograft failure, 145 (79.7%) patients returned to HD and 37 (20.3%) to
PD. Twenty-three patients (12.6%) died over the median 69.1 months duration of follow-
up. During the observation period, 16 HD (11%) and 7 PD (8.9%) patients died. The
survival rates of PD patients at 1 year were 91.2% and 84.4%, respectively, at 1 and 3
years, and those of HD patients 94.8% and 88.9%. There was no significant difference
in the survivals of the 2 groups.
Conclusions. The study suggests that the outcome of patients starting PD after
kidney transplant failure was similar to those starting HD. Therefore, PD can be
regarded to be a good treatment option for patients returning to dialysis after kidney
transplant failure.
Department
Dept. of Internal Medicine (내과학)
Kidney Institute (신장연구소)
Publisher
School of Medicine
Citation
G.W. Kang et al. (2013). Comparison of Peritoneal Dialysis and Hemodialysis After Kidney Transplant Failure. Transplantation Proceedings, 45(8), 2946–2948. doi: 10.1016/j.transproceed.2013.08.035
Type
Article
ISSN
0041-1345
DOI
10.1016/j.transproceed.2013.08.035
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/34688
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Internal Medicine (내과학)
3. Research Institutues (연구소) > Kidney Institute (신장연구소)
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