Dengue fever is a signiﬁcant health problem for international travelers to all endemic area.
Dengue fever is characterized by a sudden onset of fever, headache, rash, myalgia, and
joint pain. Infection with the dengue virus is detrimental to a immunosuppressed renal
transplant patients. Herein we report a 29-year-old woman living-related renal transplant
recipient returning from Southeast Asia with dengue fever presenting as acute colitis. The
patient traveled to Southeast Asia for 1 week. She developed watery diarrhea in the second
week after the onset of symptoms of dengue fever. Laboratory ﬁndings were leukopenia,
thrombocytopenia, and elevated serum transaminase levels. Sigmoidoscopic features
showed nonspeciﬁc acute colitis. She improved after 10 days of hospitalization with
intensive supportive care and continuous tacrolimus monotherapy. Altered clinical symp-
toms are manifested in immunologically naïve adults. Manifestation of unusual symptoms
does not exclude dengue virus infection in renal transplant recipients.