Clinical Features and Survival Outcomes in Patients with Multiple Myeloma: Analysis of Web-Based Data from the Korean Myeloma Registry
- Affiliated Author(s)
- 도영록
- Alternative Author(s)
- Do, Young Rok
- Journal Title
- Acta Haematologica.
- ISSN
- 0001-5792
- Issued Date
- 2009
- Abstract
- Aim: The Korean Multiple Myeloma Working Party performed
a nationwide registration of multiple myeloma patients
via a web-based data bank system. Methods: We retrospectively
analyzed registered data from 3,209 patients
since 1999. Results: The median overall survival (OS)
was 50.13 months (95% confidence interval: 46.20–54.06
months). Patients ^ 40 years demonstrated a longer OS than
patients 1 65 years of age (median OS 71.13 vs. 36.73 months,
p ! 0.001). Patients who received novel agents at any time
during their treatments showed a longer OS than patients
who did not (median OS 42.23 vs. 55.50 months, p ! 0.001).
Response to treatment was associated with OS, with tandem
autologous stem cell transplantation (SCT) producing longer
OS than single autologous SCT. Conclusions: We demonstrated
associations between survival outcomes and
treatment modalities as well as baseline disease characteristics
in a registry of multiple myeloma patients using a webbased
data analysis. Copyright © 2009 S. Karger AG, Basel
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