Fatty marrow conversion of the proximal femoral metaphysis in transient bone marrow edema syndrome

Authors
Shin-Yoon KimKyung-Hoi KooKuen-Tak SuhYong-Sik KimYoon-Je ChoByung-Woo MinYong-Chan HaJung-Ah Choi
Department
Dept. of Orthopedic Surgery (정형외과학)
Issue Date
2005
Citation
Archives of Orthopaedic and Trauma Surgery, Vol.125(6) : 390-395, 2005
ISSN
0936-8051
Abstract
Introduction In the proximal femoral metaphysis, hematopoietic marrow is predominant during the adult stage of life. The conversion of hematopoietic marrow to fatty marrow in the proximal femoral metaphysis has been suggested as an etiologic factor of ischemia in the pathogenesis of femoral head osteonecrosis. To determine whether the chronology of fatty marrow conversion of the proximal femoral metaphysis is related to transient bone marrow edema syndrome of the hip, a case control study was conducted on 10 patients with the disease. Materials and methods There were 8 men and 2 women with a mean age of 33 years (range 19–45 years). The 10 patients were matched with 20 controls for gender and age (5-year range). T1- weighted MRI scans of their hips were reviewed. Marrow of the greater trochanter becomes fatty before puberty, and thus, the greater trochanter can be used as a built-in control. The signal intensity of the proximal femoral metaphysis was compared to that of the greater trochanter. Results In all patients, the signal intensity of the proximal femoral metaphysis was isointense (fatty marrow) relative to that of the greater trochanter. In control subjects, the signal intensity was isointense in 8 (40%) and hypointense (hematopoietic marrow) in 12 (60%) (p<0.05). Conclusion The current study shows that the proximal femoral metaphysis is predominantly fatty in transient bone marrow edema syndrome. The conversion of hematopoietic to fatty marrow is known to correlate with decreases in intramedullary blood flow. Thus, the current study suggests that an ischemia of the proximal femur secondary to fatty marrow conversion of the proximal femoral metaphysis might be a cause of transient bone marrow edema syndrome of the hip. Keywords Hip Æ Proximal femoral metaphysis Æ Bone marrow edema Æ MRI
URI
http://kumel.medlib.dsmc.or.kr/handle/2015.oak/35080
Appears in Collections:
1. Journal Papers (연구논문) > 1. School of Medicine (의과대학) > Dept. of Orthopedic Surgery (정형외과학)
Keimyung Author(s)
민병우
Full Text
https://link.springer.com/article/10.1007%2Fs00402-005-0824-4
File in this Item
 사서에게 요청하기
Export
RIS (EndNote)
XLS (Excel)
XML


qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

BROWSE