A Multicenter observational study on the role of comorbidities in the recurrent episodes of benign paroxysmal positional vertigo
- Alessandro De Stefano; Francesco Dispenza; Hamlet Suarez; Nicolas Perez-Fernandez; Raquel Manrique-Huarte; Jae Ho Ban; Min Beom Kim; Michael Strupp; Katharina Feil; Carlos A. Oliveira; Andres L. Sampaio; Mercedes F.S. Araujo; Fayez Bahmad Jr; Mauricio M. Gananc; Fernando F. Gananc; Ricardo Dorigueto; Hyung Lee; Gautham Kulamarva; Navneet Mathur; Pamela Di Giovanni; Anna Grazia Petruccim; Tommaso Staniscia; Leonardo Citraro; Adelchi Croce
- Dept. of Neurology (신경과학)
- Issue Date
- Auris Nasus Larynx, Vol.41(1) : 31-36, 2014
- Objective: Primary objective of this study was to find a statistical link between the most worldwide
comorbidities affecting the elderly population (hypertension, diabetes, osteoarthrosis, osteoporosis and
depression) and recurrent episodes of BPPV. Secondary objective was defining possible ‘‘groups of risk’’ for
people suffering recurrent positional vertigo related to the presence of a well documented comorbidity.
Methods: This was an observational, cross-sectional, multicenter, spontaneous, non-pharmacological study.
and Neurology, referring Centers for positional vertigo evaluation, were retrospectively collected.
Results: Regarding evaluated comorbidities (hypertension, diabetes, osteoarthrosis, osteoporosis and
depression), data analysis showed the presence of at least one comorbid disorder in 216 subjects (19.8%)
and 2 or more in 408 subjects (37.4%). Moreover there was a statistical significant difference between the
number of comorbidities and the number of recurrences, otherwise said as comorbidity disorders
increased the number of relapses increased too.
Conclusion: The presence of a systemic disease may worsen the status of the posterior labyrinth causing
a more frequent otolith detachment. This condition increases the risk for patients suffering BPPV to have
recurrent episodes, even if correctly managed by repositioning maneuvers. The combination of two or
more of aforementioned comorbidities further increases the risk of relapsing BPPV, worsened by the
presence of osteoporosis. On the basis of this results it was possible to define ‘‘groups of risk’’ useful for
predicting BPPV recurrence in patients with one or more comorbidity.
2013 Published by Elsevier Ireland Ltd.
- Appears in Collections:
- 1. Journal Papers (연구논문) > 1. School of Medicine (의과대학) > Dept. of Neurology (신경과학)
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