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Small Intestinal Submucosa Plug for Closure of Dilated Nephrostomy Tracts: A Pilot Study in Swine

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Author(s)
김영환
Alternative Author(s)
Kim, Young Hwan
Publication Year
2010
Abstract
The aim of this study was to evaluate efficacy of a plug made of small intestinal submucosa (SIS) for closure of dilated nephrostomy tract in the kidney after nephroscopy. Ten kidneys in 5 swine had nephrostomy tracts dilated up to 8 mm. The SIS plug was placed into the dilated renal cortex under nephroscopic control. Follow-up arteriograms, retrograde pyelograms, and macroscopic and histologic studies at 24 h (n = 4), 6 weeks (n = 2), and 3 months (n = 4) were performed to evaluate the efficacy of the plug. The SIS plug effectively closed the dilated nephrostomy tract. Follow-up studies showed minimal changes of the kidneys, except for 1 small infarction, regarding inflammatory and foreign-body reactions and progressive scarring of the SIS. SIS plug is effective for occlusion of dilated nephrostomy tract after nephroscopy. Its efficacy should be compared with other therapeutic options.


Keywords
Biomaterial – Small Intestinal submucosa – Interventional procedures – Embolization – Kidneys
Department
Dept. of Radiology (영상의학)
Publisher
School of Medicine
Citation
Cardiovascular and Interventional Radiology, Vol.33(3) : 596-600, 2010
Type
Article
ISSN
0174-1551
DOI
10.1007/s00270-010-9811-4
URI
http://kumel.medlib.dsmc.or.kr/handle/2015.oak/35364
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