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Usefulness of Tissue Doppler Imaging-Myocardial Performance Index in the Evaluation of Diastolic Dysfunction and Heart Failure With Preserved Ejection Fraction

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Author(s)
Hyungseop KimHyuck-Jun YoonHyoung-Seob ParkYun-Kyeong ChoChang-Wook NamSeung-Ho HurYoon-Nyun KimKwon-Bae Kim
Keimyung Author(s)
Kim, Hyung SeopYoon, Hyuck JunPark, Hyoung SeobCho, Yun KyeongNam, Chang WookHur, Seung HoKim, Yoon NyunKim, Kwon Bae
Department
Dept. of Internal Medicine (내과학)
Journal Title
Clinical Cardiology
Issued Date
2011
Volume
34
Issue
8
Abstract
Background: In heart failure with preserved ejection fraction (HFPEF), physiological abnormalities are not solely
restricted to diastolic function. Because the tissue Doppler imaging (TDI)-derived myocardial performance
index (MPI) offers the advantage of recording systolic and diastolic tissue velocity simultaneously in the same
cardiac cycle, this study aimed to determine whether TDI-MPI is an informative index for assessing HFPEF,
compared with conventional echo parameters.
Hypothesis: In patients with HFPEF, TDI-MPI would be an independent predictor for adverse cardiac events.
Methods: Among 408 patients who had diastolic dysfunction without heart failure (HF) or HFPEF, cardiac
function was evaluated by mitral flow (MF) or TDI-MPI. During the median follow-up of 32 months, clinical
outcomes, which were defined as the composite of cardiovascular death and admission for HF, were assessed.
Results: Mean MF and TDI-MPI were significantly greater in the HFPEF group. TDI-MPI rather than MF had a
significant correlation with N-terminal pro-brain natriuretic peptide level. The area under the receiver operating
characteristic curve of TDI-MPI for the detection of HFPEF was 0.86. With regard to clinical outcomes, 31 events
were identified during follow-up periods. On a multivariate analysis, TDI-MPI >0.66 was the best prognostic
predictor of events and provided incremental predictive value.
Conclusions: Compared to MF-MPI, TDI-MPI may be a more useful parameter for the evaluation of patients
with HFPEF
Keimyung Author(s)(Kor)
김형섭
윤혁준
박형섭
조윤경
남창욱
허승호
김윤년
김권배
Publisher
School of Medicine
Citation
Hyungseop Kim et al. (2011). Usefulness of Tissue Doppler
Imaging-Myocardial Performance Index
in the Evaluation of Diastolic Dysfunction
and Heart Failure With Preserved Ejection
Fraction. Clinical Cardiology, 34(8), 494–499. doi: 10.1002/clc.20932
Type
Article
ISSN
0160-9289
DOI
10.1002/clc.20932
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/35443
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Internal Medicine (내과학)
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