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Comparison of Long-term Outcomes Following Sirolimus-eluting Stent vs Paclitaxel-eluting Stent Implantation in Patients with Long Calcified Coronary Lesions

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Affiliated Author(s)
허승호조윤경남창욱김형섭한성욱김윤년김권배박희준
Alternative Author(s)
Hur, Seung HoCho, Yun KyeongNam, Chang WookKim, Hyung SeopHan, Seong WookKim, Yoon NyunKim, Kwon BaePark, Hee Jun
Journal Title
Clinical Cardiology
ISSN
0160-9289
Issued Date
2009
Abstract
Background


Although previously reported studies on coronary calcification mainly focused on its presence or absence in discrete focal target lesions, calcified coronary lesions (CCL) angiographically present as diffuse long lesions in some patients. The aim of our study was to evaluate the long-term efficacy of sirolimus-eluting stents (SES) and paclitaxel-eluting stents (PES) on long CCL.


Methods


A total of 122 patients with 134 lesions (77 patients with 88 lesions for SES and 45 patients with 46 lesions for PES) were enrolled from 3 centers. Long CCL was defined visually as a culprit lesion with type B or C that was mainly due to coronary calcification with > 20 mm in total length by coronary angiography. Clinical follow-up was performed at 1 year and angiographic follow-up at 6 to 9 months after procedure. Major adverse coronary events (MACE) were defined as all-cause death, myocardial infarction (MI), and repeat target-lesion revascularization (TLR).


Results


There were no statistically significant differences in baseline, procedural, or angiographic characteristics and in 1-year rates of all-cause death, MI, and TLR between the 2 groups (all P = NS [not significant]). Likewise, the cumulative incidence of MACE at 1 year was similar between the 2 groups (7.8% of patients in the SES group vs 4.4% of patients in the PES group, respectively, P = NS). In patients who underwent follow-up angiography, the angiographic binary restenosis rate was 6.2% in the SES group vs 12.1% in the PES group, respectively (P = NS).


Conclusion


In patients with long CCL, both SES and PES were comparably effective in either angiographic or clinical long-term outcomes. Copyright © 2009 Wiley Periodicals, Inc.
Department
Dept. of Internal Medicine (내과학)
Dept. of Biomedical Engineering (의용공학과)
Publisher
School of Medicine
Citation
Seung-Ho Hur et al. (2009). Comparison of Long-term Outcomes
Following Sirolimus-eluting Stent vs
Paclitaxel-eluting Stent Implantation in
Patients with Long Calcified Coronary
Lesions. Clinical Cardiology, 32(11), 633–638. doi: 10.1002/clc.20591
Type
Article
ISSN
0160-9289
DOI
10.1002/clc.20591
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/35483
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Biomedical Engineering (의용공학과)
1. School of Medicine (의과대학) > Dept. of Internal Medicine (내과학)
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