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Gray matter alteration in patients with restless legs syndrome: a voxel-based morphometry study

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Affiliated Author(s)
장혁원구정훈조용원
Alternative Author(s)
Chang, Hyuk WonKu, Jeong HunCho, Yong Won
Journal Title
Clinical Imaging
ISSN
0899-7071
Issued Date
2015
Abstract
The purpose of this study was to demonstrate whether or not restless legs syndrome (RLS) is associated with any morphological change in gray matter. Forty-six RLS subjects and 46 controls were enrolled. We performed voxel-based morphometry analysis and compared the results of the two groups. The RLS subjects showed significant regional decreases of gray matter volume in the left hippocampal gyrus, both parietal lobes, medial frontal areas and cerebellum (uncorrected, P< .001). We found that RLS patients showed structural alteration in the brain and alterations in certain parts of the brain in RLS patients are relevant to RLS.

Keywords
Restless legs syndrome;
MRI;
Voxel-based morphometry;
Gray matter
Department
Dept. of Radiology (영상의학)
Dept. of Biomedical Engineering (의용공학과)
Dept. of Neurology (신경과학)
Publisher
School of Medicine
Citation
Yongmin Chang et al. (2015). Gray matter alteration in patients with restless legs syndrome:
a voxel-based morphometry study. Clinical Imaging, 39(1), 20–25. doi: 10.1016/j.clinimag.2014.07.010
Type
Article
ISSN
0899-7071
DOI
10.1016/j.clinimag.2014.07.010
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/35492
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Biomedical Engineering (의용공학과)
1. School of Medicine (의과대학) > Dept. of Neurology (신경과학)
1. School of Medicine (의과대학) > Dept. of Radiology (영상의학)
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