계명대학교 의학도서관 Repository

Comparison of Clinical Outcomes Among Different Endoscopic Resection Methods for Treating Colorectal Neoplasia

Metadata Downloads
Affiliated Author(s)
김은수조광범박경식장병국정우진황재석
Alternative Author(s)
Kim, Eun SooCho, Kwang BumPark, Kyung SikJang, Byoung KukChung, Woo JinHwang, Jae Seok
Journal Title
Digestive Diseases and Sciences
ISSN
0163-2116
Issued Date
2013
Abstract
Background/Aim Endoscopic treatments of colorectal
neoplasms have yet to be standardized. This study aimed to
compare efficacy and tolerability of different endoscopic
resection methods for colorectal epithelial tumors.
Methods Patients with non-pedunculated colorectal
tumors undergoing endoscopic treatments were consecutively
enrolled, and their medical records were reviewed
retrospectively. The resection methods were classified into
three groups: endoscopic mucosal resection with circumferential
precutting (EMR-P), endoscopic submucosal dissection
with snaring (ESD-S), and endoscopic submucosal
dissection alone (ESD). We compared en bloc resection,
pathological complete resection, and complications associated
with these methods.
Results Overall, 206 lesions from 203 patients were
included in the study (mean size 25.2 ± 10.1 mm). The
number of lesions treated with EMR-P, ESD-S, and ESD
was 91 (44.2 %), 57 (27.7 %), and 58 (28.2 %), respectively.
There was a significant difference in both the en
bloc resection rates (EMR-P, 61.5 %; ESD-S, 64.9 %;
ESD, 96.6 %; p = 0.001) and complete resection
rates (EMR-P, 51.6 %; ESD–S, 54.4 %; ESD, 75.9 %;
p = 0.009). Bleeding and perforation were less frequently
observed in the EMR-P group. In the subgroup-analysis of
lesions less than 20 mm, however, these differences were
not observed.
Conclusions All endoscopic resection methods, including
EMR-P, ESD-S, and ESD, were effective and safe for the
treatment of colorectal neoplasms. Technically demanding
ESD with high en bloc and complete resection rate should
be reserved for the suspicious cancer lesion, which requires
the precise histological evaluation. EMR-P with good
feasibility can be considered an alternative to ESD for the
lesions less than 20 mm.
Keywords Colon neoplasm Resection Endoscopy
Treatment
Department
Dept. of Internal Medicine (내과학)
Publisher
School of Medicine
Citation
Yun Jung Kim et al. (2013). Comparison of Clinical Outcomes Among Different Endoscopic
Resection Methods for Treating Colorectal Neoplasia. Digestive Diseases and Sciences, 58(6), 1727–1736. doi: 10.1007/s10620-013-2560-x
Type
Article
ISSN
0163-2116
DOI
10.1007/s10620-013-2560-x
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/35592
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Internal Medicine (내과학)
공개 및 라이선스
  • 공개 구분공개
  • 엠바고Forever
파일 목록

Items in Repository are protected by copyright, with all rights reserved, unless otherwise indicated.