계명대학교 의학도서관 Repository

Long-Term Clinical Outcomes according to initial management and thrombolysis in myocardial infarction risk score in patients with acute non-ST-segment elevation myocardial infarction

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Affiliated Author(s)
허승호
Alternative Author(s)
Hur, Seung Ho
Journal Title
Yonsei Medical Journal
ISSN
0513-5796
Issued Date
2010
Abstract
PURPOSE: There is still debate about the timing of revascularization in patients with acute non-ST-segment elevation myocardial infarction (NSTEMI). We analyzed the long-term clinical outcomes of the timing of revascularization in patients with acute NSTEMI obtained from the Korea Acute Myocardial Infarction Registry (KAMIR).

MATERIALS AND METHODS:

2,845 patients with acute NSTEMI (65.6 +/- 12.5 years, 1,836 males) who were enrolled in KAMIR were included in the present study. The therapeutic strategy of NSTEMI was categorized into early invasive (within 48 hours, 65.8 +/- 12.6 years, 856 males) and late invasive treatment (65.3 +/- 12.1 years, 979 males). The initial- and long-term clinical outcomes were compared between two groups according to the level of Thrombolysis In Myocardial Infarction (TIMI) risk score.

RESULTS:

There were significant differences in-hospital mortality and the incidence of major adverse cardiac events during one-year clinical follow-up between two groups (2.1% vs. 4.8%, p < 0.001, 10.0% vs. 13.5%, p = 0.004, respectively). According to the TIMI risk score, there was no significant difference of long-term clinical outcomes in patients with low to moderate TIMI risk score, but significant difference in patients with high TIMI risk score (>or= 5 points).

CONCLUSIONS:

The old age, high Killip class, low ejection fraction, high TIMI risk score, and late invasive treatment strategy are the independent predictors for the long-term clinical outcomes in patients with NSTEMI.


KEYWORDS:

Myocardial infarction; TIMI risk score; invasive treatment; non-ST-segment elevation; prognosis
Department
Dept. of Internal Medicine (내과학)
Publisher
School of Medicine
Citation
Hae Chang Jeong et al. (2010). Long-Term Clinical Outcomes according to initial management and thrombolysis in myocardial infarction risk score in patients with acute non-ST-segment elevation myocardial infarction. Yonsei Medical Journal, 51(1), 58–68. doi: 10.3349/ymj.2010.51.1.58
Type
Article
ISSN
0513-5796
DOI
10.3349/ymj.2010.51.1.58
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/37253
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Internal Medicine (내과학)
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