Formula fed twin infants with recurrent hypocalcemic seizures with vitamin D deficient rickets and hyperphosphatemia
- Affiliated Author(s)
- 이희정; 심예지; 김준식; 김흥식
- Alternative Author(s)
- Lee, Hee Jung; Shim, Ye Jee; Kim, Joon Sik; Kim, Heung Sik
- Journal Title
- Annals of Pediatric Endocrinology & Metabolism
- ISSN
- 2287-1012
- Issued Date
- 2015
- Abstract
- Vitamin D deficient rickets is generally known to occur in breast fed infants. And excessive phosphate ingestion is a main cause of late onset hypocalcemia in formula fed infants. Here we introduce 45-day-old formula fed hypocalcemic twins with recurrent seizure attacks. They were diagnosed as having both of vitamin D deficient rickets and hyperphosphatemia. Radiologic findings indicated mild rickets and the twins were treated with calcium and alfacalcidol. After 3-5 months of oral supplementation, medication was discontinued in both twins. They showed normal growth and calcium, phosphorus, and vitamin D levels during the 6-month follow-up period. Twins can be at risk for hypocalcemia because of their high risk of vitamin D deficiency, low birth weight, and premature birth. Therefore twin pregnant women need ingestion of sufficient vitamin D and calcium.
Keywords: Twins; Vitamin D deficiency; Hypocalcemia; Seizures; Rickets
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