급성신부전으로 발현된 신혈관 및 신간질의 아밀로이드증 1예

Abstract

We report a case of predominantly vascular and interstitial amyloid deposition in the kidney in a patient who presented with acute renal failure and without overt proteinuria. A 59 year-old male patient was admitted to the hospital because of general weakness, dyspnea, decreased urine output and generalized edema. Laboratory findings included BUN 49mg/dL, serum creatinine 6.7mg/dL, and serum albumin 3.7g/dL. His urinalysis showed albumin( — )， RBC 3/HPF, and WBC 6/HPF. Percutaneous renal biopsy revealed a predominantly vascular and interstitial deposition of amyloid, and had no glomerular amyloid deposition. His renal funtion improved with symptomatic treatment to serum creatinine level of 1.2mg/dL at 1 month after diagnosis.