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Complete Nucleotide Sequence of Cytochrome P450 2E1 Expressed in the Rat Brain

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Affiliated Author(s)
김나현
Alternative Author(s)
Kim, Na Hyun
Journal Title
대한의생명과학회지
ISSN
1738-3226
Issued Date
2005
Abstract
From the RT-PCR amplifications using mRNA templates isolated from Sprague-Dawley rat brains, we isolated a cDNA fragment of 1,524 bp which covered the full coding information of the rat brain CYP2E1. Its nucleotide sequence was identical to the previously reported rat liver CYP2E1 mRNA except for the difference of one base (A to C at the nucleotide position 73). This difference also altered the amino acid Lys to Gln. However, no insertion or deletion of nucleotide(s) which could alter the reading frame was found within the structure of this rat brain CYP2E1. This study should provide the molecular basis regarding the pathophysiological function of CYP2E1 in the brain.
Department
Dept. of Nursing (간호학)
Publisher
College of Nursing
Citation
Song Woo Shin et al. (2005). Complete Nucleotide Sequence of Cytochrome P450 2E1 Expressed in the Rat Brain. 대한의생명과학회지, 11(2), 109–113.
Type
Article
ISSN
1738-3226
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/38306
Appears in Collections:
2. College of Nursing (간호대학) > Dept. of Nursing (간호학)
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