생체 신이식후 조기에 발생한 무뇨증에 대한 Dopamine-furosemide의 병용치료

Abstract

Five patients with abrupt onset of anuria developed at the early period of post-renal transplantation were treated with cocktail solution of large dose of furosemide (100 mg every 6 hours) and low dose dopamine (1-2 ug/Kg/min). These patients had no obstructive lesions at urinary tract and renal vessels and no abnormal mass around grafted kidney and bladder. Clinical, manifestations were similar to acute renal failure but findings of ultrasonography and renal scan could eliminate the possibility of rejection. Two of them had anomalous double renal arteries and another two were developed anuria immediately after renal scan. Restorations of urine flow were started 4 to 30 hours after dopamine-furosemide cocktail therapy. This cocktail therapy could be used in post-transplant anuria as well as acute renal failure.