성견의 좌측 일측폐이식술후 초급성 거부반응 관찰

Abstract

We experienced hyperacute rejection on the 3rd day after a single left lung transplantation in dog. The heart-lung bloc was extirpated from a donor dog(19 kg) while flushing with 4°C Modified Euro-Collin solution(5() ml/kg) and immersed in the same solution. Recipient dog(21 kg) was given oral cyclosporine(15 mg/kg) and azathioprine(1.5 mg/kg) before anesthesia and 500 mg of Solumedrol was given intravenously on induction. Left atrial anastomosis, pulmonary artery anastomosis and bronchial anastomosis was performed in this order. Continuous everting mattress suture for left atrial anastomosis was used with 5~0 prolene and then continuous over and over suture for the other two anastomoses were adopted with 5~0 prolene and 4~0 vicryl repectively. Chest X-ray was taken two times on the immediate postopertive day and 1st day postoperatively and their findings were normal.On the 1st postoperative day perfusion lung scan was made and its finding was difficult perfusion to the transplanted lung. On the 3rd postopertive day dog was expired and pathologic finding of transplated lung was hyperacute rejection.