성 성숙도 및 신체계측치와 골밀도와의 관계

Abstract

Background: Maximizing peak bone mass is advocated as a way to prevent osteoporosis. As a prerequisite to the elaboration of any preventive program aimed at rnaximizing peak bone mass, it is important to determine how the rate of skeletal growth at elinically relevant sites, such as lumbar spine(LS), femoral neck(FN), proceeds in relation to age and pubertal stages in both sexes. The present study was performed to measure bone mineral density(BMD) of Korean children and adolescents and to assess the influence of age, sex, puberty and body size on bone mineral density (BMD) during the period of bone growth. Method: Lumbar spine(LS), femoral neck(FN) BMD were measured in 199 healthy males and fernales 7~23 years of age using dual energy x-ray absorptiometry(DEXA), Tanner staging(TS) was used to assess stage of puberty. Results: Anthropometric measurements generally increased with tanner stage in both sexes. Sex differences were observed. In males, compared to females there were significantly higher in height(TS1, TS3, TS4, TS5), weight(TS1, TS3, TS5), dorsal hand skinfold thickness(TS1, TS5), and lean body mass(TS1, TS3, TS4, TS5): while in females, compared to males there were significantly higher in BMI(TS4), skinfold thickness except dorsal hand and fat %(TS3-TS5), and total fat mass(TS3, TS4)(p