Is the rapid sequence induction possible with 0.6 mg/kg rocuronium in pediatric patient?

Abstract

Background: We have investigated the possibility of rocuronium 0.6 mg/kg and timing principle application with the same dose for rapid sequence induction (RSI) in 65 children, aged 4-8 yr. Methods: Sixty five patients were randomly assigned to one of two groups; Group A (n 31, timing principle application) received rocuronium (0.6 mg/kg) followed by administration of propofol (2.5 mg/kg), and group B (n 36) received rocuronium (0.6 mg/kg) after administration of propofol. Intubation was assessed at 60 seconds just after administration of last injectants. Intubating conditions (jaw relaxation, vocal cord movement, and response to tracheal intubation) were evaluated as excellent, good, fair and poor. Results: Excellent intubation conditions were obtained in 87% in group A and 61% in group B. However, clinically acceptable intubation conditions which means excellent and good did not show any significant difference as 100% (group A) and 99% (group B). Conclusions: In cases of pediatiric patients undergoing elective surgery, RSI was possible irrespective of the use of timing principle. (Korean J Anesthesiol 2010; 58: 20~24)