악성 신경 교종 환자에서 High-Activity Iridium-192를 이용한 종양내삽입 방사선 치료의 임상분석

Abstract

Interstitial irradiation using high-activity Iridium-I92 sources was studied clinically to treat supratentorial malignant astrocytomas(including glioblastoma multifrome). As of 1988, in attempt to define the efficacy of this technique in patients with more extensive disease, we treated patients less rigid selection criteria. 15 eligible patients have been approached and ten have accepted randomization for follow-up study over two years. Pathology was anaplastic astrocytoma in 5 patients, glioblastoma multiforme in 5 patients. Mean survival of patients treated with this procedure was 18.4 months. Continued investigation will determine which-patient may benefit from this techique.