전자간증과 정상 임신 군에서의 혈청 내 중성지방, 유리 지방산, 인슐린 값의 비교

Abstract

We examined the hypothesis that serum insulin, triglyceride, lipoprotein and free fatty acid concentrations are increased in preeclamptic women relative to normal pregnant women. Predelivery venous blood samples were collected from twenties women with preeclampsia and twenties women with uncomplicated pregnancies after 8 hour fast. Sera were analysed for concentrations of triglycerides, free fatty acids, total cholesterol, high-density lipoprotein, low-density lipoprotein, uric acid and insulin. Antepartum triglycerides, free fatty acids, and insulin concentrations were increased in women with preeclampsia relative to normal pregnant women. High-density lipoprotein, low-density lipoprotein, total cholesterol, Apolipoprotein A, and Apolip-oprotein B concentrations did not differ between two group. This study has demonstrated that triglycerides, free fatty acid and insulin, but not lipoprotein, are increased in preeclampsia. We speculated that these interactions may contribute to endothelial cell dysfunction in preeclampsia. It may as a marker of the pathogenic process.