다양한 은-화합물이 첨가된 의치상 레진의 칸디다균에 대한 항균 특성 및 물성에 관한 연구

Abstract

The purpose of this study was to evaluate antifungal effect against Candida albicans and physical characteristics of silver (Ag) - contained denture acrylic base. The heat-polymerized denture acrylic (Vertex-RS®? Dentimex, Zeist, Holland) specimens, with 4 different incorporated patterns of silver as Ag nano-particles (Ag°), AgNO3 , Ag°-chitosan and AgNCVchitOsan，were fabricated with the concentrations of 0.2, 1.0 and 5.0 % of Ag. When compared with control (0 % Ag) after 24-hour incubation, significant reduced colony forming unit was found in 1.0 % (33.7〜 56.5 %) and 5.0% (69.0〜 76.3 %) on modified Ag-denture base acrylic (p ( 0.01). There were extremely low release Of silver ions (Ag+) from Ag-denture acrylic as compared with initial amount Of silver incorporated. Physical characteristics of Ag-denture acrylic were clinically reliable in flexural strength, conversion rate and surface examination on SEM except in color stability.