Carbamazepine에 의해 발생된 것으로 사료되는 항경련제 과민성 증후군 1예
- 박석열; 김주용; 김창욱; 김병천; 이규석
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- Anticonvulsant Hypersensitivity syndrome; Carbamazepine
- Anticonvulsant hypersensitivity syndrome is a life threatening immunologic reaction of anticonvulsants therapy such as phenytoin, phenobarbital, or carbamazepine, characterized by multiple abnormalities ssuch as fever, rash, lymphadenopathy, acute hepatocellular injury, leukocytosis, and eosinophilia. We report a case of anticonvulsant hypersensitivity syndrome thought to be caused by the use of carbamazepine in a 65-year-old male. He developed erythematous skin eruption four weeks after beginning therapy with carbamazepine. The clinical, laboratory and histologic findings of this patient were compatible with anticonvulsant hypersensitivity syndrome.
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