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Methazolamide가 원인으로 추정되는 Stevens-Johnson 증후군 5예

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Affiliated Author(s)
이규석조재위
Alternative Author(s)
Lee, Kyu SukCho, Jae We
Journal Title
대한피부과학회지
ISSN
0494-4739
Issued Date
2013
Keyword
MethazolamideStevens-Johnson syndrome
Abstract
Recently, Stevens-Johnson syndrome associated with methazolamide has been reported in Koreans, more frequently. Methazolamide is a carbonic anhydrase inhibitor commonly used for lowering intraocular pressure in glaucoma and
other ophthalmologic diseases. We reported five cases of Stevens-Johnson syndrome induced by methazolamide. All patients showed atypical clinical manifestations, compared to classical Stevens-Johnson syndrome. Methazolamide
induced Stevens-Johnson syndrome showed scattered or confluent maculopapular eruptions initially, which are similar to morbiliform drug eruption with mild lip erosion and palmar erythema. Even though there was no skin erosion
initially, it showed rapid progression to severe erosion on the trunk and palmoplantar erythema within 5 to 7 days. Therefore, our data indicated that methazolamide induced Stevens-Johnson syndrome should be checked for a patient
who has a history of ophthalmologic treatment with a drug eruption like skin lesion.
Alternative Title
Five Cases of Stevens-Johnson Syndrome May Be Associated with Methazolamide Treatment
Department
Dept. of Dermatology (피부과학)
Publisher
School of Medicine
Citation
한길 et al. (2013). Methazolamide가 원인으로 추정되는 Stevens-Johnson 증후군 5예. 대한피부과학회지, 51(5), 329–334.
Type
Article
ISSN
0494-4739
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/39785
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Dermatology (피부과학)
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