경구 Cyclosporin과 혈소판 풍부 혈장 병합요법을 적용한 괴저고름피부증 치험 1예

Other Titles
A Case of Pyoderma Gangrenosum Treated by Combination Therapy with Oral Cyclosporin and Platelet Rich Plasma
Authors
강민철김성애이규석조재위
Department
Dept. of Dermatology (피부과학)
Issue Date
2010
Citation
대한피부과학회지, Vol.48(4) : 313-317, 2010
ISSN
0494-4739
Abstract
Pyoderma gangrenosum is an uncommon, chronic, neutrophilic ulcerative condition of uncertain pathophysiology. Although the main therapy is the systemic administration of high doses of steroid therapy, many other therapeutic modalities have been widely used. Combination therapy with systemic corticosteroids and cyclosporin has proven effective in many cases. However, prolonged therapy is associated with significant side effects. Platelet rich plasma (PRP) has many growth factors such as PDGF (platelet derived growth factor), VEGF (Vascular endothelial growth factor) and FGF (fibroblast growth factor). Recently, PRP has been gaining attention in the treatment of recalcitrant cutaneous ulcers. An 82-year-old woman presented with recurrent painful ulcers on the dorsal surface of both hands. She had been treated with systemic steroids, cyclosporine, minocylclin, triamcinolone intradermal injection and PRP. Thus, we report a case of pyoderma gangrenosum that was successfully treated with combination therapy of oral cyclosporine and PRP.
Keywords
CyclosporinPlatelet rich plasmaPyoderma gangrenosum
URI
http://kumel.medlib.dsmc.or.kr/handle/2015.oak/39796
Appears in Collections:
1. Journal Papers (연구논문) > 1. School of Medicine (의과대학) > Dept. of Dermatology (피부과학)
Keimyung Author(s)
김성애; 이규석; 조재위
Full Text
http://kiss.kstudy.com/thesis/thesis-view.asp?key=2836991
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