경피증양 피부 소견을 보인 유암 증후군 1예

Other Titles
A Case of Carcinoid Syndrome with a Scleroderma-like Lesion
Authors
박영도김성애조재위이규석
Department
Dept. of Dermatology (피부과학)
Issue Date
2009
Citation
대한피부과학회지, Vol.47(9) : 1054-1059, 2009
ISSN
0494-4739
Abstract
Carcinoid syndrome exhibits a constellation of symptoms typically exhibited by patients with carcinoid tumors that produce neuroendocrine mediators, including serotonin. Carcinoid syndrome is diagnosed by increasing urinary 5-hydroxyindoleacetic acid and manifestations of gastrointestinal tract, respiratory, cardiovascular, and skin involvement, which occurs in <10% of patients. Cutaneous manifestations are flushing, telangiectasias, pellagra dermatitis, and scleroderma-like lesions, which are relatively rare. A 60-year-old woman presented with sclerotic skin lesions on both legs. On examination, a 10×10 cm solid mass was palpable on the right lower abdomen, and she had facial flushing and telangiectasia, but Raynaud's phenomenon was absent. The urinary 5-hydroxyindoleacetic acid was elevated (68.2 mg/day). Abdominal and pelvic CT scans showed a right ovarian tumor which was diagnosed as a carcinoid tumor by CT-guided needle biopsy. Thus, we report, for the first time, a case of carcinoid syndrome with scleroderma-like lesions in a Korean patient. If facial flushing and a scleroderma-like lesion present together, one should consider a carcinoid tumor.
Keywords
Carcinoid syndromeSclerodermaSerotonin
URI
http://kumel.medlib.dsmc.or.kr/handle/2015.oak/39797
Appears in Collections:
1. Journal Papers (연구논문) > 1. School of Medicine (의과대학) > Dept. of Dermatology (피부과학)
Keimyung Author(s)
김성애; 조재위; 이규석
Full Text
http://kiss.kstudy.com/thesis/thesis-view.asp?key=2807990
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