An isotopic response is the occurrence of a new skin disorder at the site of another, unrelated, or already healed skin disease. The most common course of an isotopic response is a herpes zoster disease. Verrucous hyperplasia is
known as a reactive hyperplastic condition, characterized morphologically by numerous, warty, coalescent papules and plaques. We report here on a case of verrucous hyperplasia developed at the site of healed herpes zoster, which
is an unusual type of isotopic response.