비전형적인 임상 양상을 보인 미만성 피부전이암 1예
- 류영욱; 김병천; 이규석
- Alternative Author(s)
- Ryoo, Young Wook; Kim, Byung Chun; Lee, Kyu Suk
- Publication Year
- Extensive Metastatic Carcinoma, Unusual
- Cutaneous metastases from Internal carcinomas are relatively rare. We report a case of cutaneous metastasis believed t.o originate from primary lung carcinoma in a 69-year-old male patient. The patient presented with localized well defined multiple variable sized, hard eryt,hematous papules, nodules and pustules on the right chest, back and upper arm. Biopsy specimens from the nodules upper chest revealed scatt,ered islands of tumor cells and fi brosis of the dermis. To evaluate the role of p53 protein in the development of skin tumors, we examed p53 expres sion at protein level by imnunoperoxidase stain using monoclonal antimouse human p53 antibody on paraffin embeded tissues The patient died after four months from the appearance of cutaneous lesions.
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