Atypical Spitz’s nevus is a rare spitzoid melanocytic proliferations with an uncertain malignant potential. Atypical Spitz’s nevus have overlapping features of both Spitz nevi and spitzoid melanoma, and consequently, generate
controversies with diagnosis and management. Herein, we report a case of atypical Spitz’s nevus developing on the lower right leg of a 46-year-old man. Histologically, the lesion shows numerous uniform nests of spindle cells and
epithelioid cells in the dermis. The lesion had a high Ki-index, prominent cellular density, but not enough to consider a diagnosis of melanoma. The nevus was removed by total excisions. No recurrences or metastases were
detected during the follow-up period of 6 months.