Keimyung Medical Journal, Vol.27(1) : 69-73-69-73, 2008
Sheehan's syndrome is a postpartum hypopituitarism due to acute ischemic necrosis
of the anterior pituitary gland secondary to severe postpartum bleeding and shock. Generally; it is
diagnosed several months to years after the last delivery complicated with severe postpartum
bleeding. However; we experienced a case of abrupt onset Sheehan's syndrome with acute
adrenal insufficiency occurring 20 days after delivery with severe bleeding. Hormonal study
revealed decreased cortisol and growth hormone response to insulin-induced hypoglycemia. The
patient recovered dramatically with glucocorticoid replacement therapy.