리툭시맙으로 효과적으로 치료한 스테로이드 비반응 하시모토뇌병증
- Affiliated Author(s)
- 조용원
- Alternative Author(s)
- Cho, Yong Won
- Journal Title
- 대한신경과학회지
- ISSN
- 1225-7044
- Issued Date
- 2018
- Keyword
- Encephalopathy; Thyroid hormones; Rituximab; Glucocorticoids
- Abstract
- Hashimoto’s encephalopathy is a rare autoimmune disease, with symptoms of encephalopathy and high titers of serum anti-thyroid antibodies. Current diagnostic criteria include corticosteroid responsiveness, but in some cases, they are refractory to corticosteroids. In steroid non-responders, other immunomodulatory therapies could be applied. Recently, Rituximab is reported as a safe and effective treatment for Hashimoto’s encephalopathy. We report a 50-year-old woman with Hashimoto’s encephalopathy presented with confusion and catatonia who was refractory to corticosteroid and immunoglobulin but effectively treated with rituximab.
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