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A new risk score for ventricular tachyarrhythmia in acute myocardial infarction with preserved left ventricular ejection fraction

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Affiliated Author(s)
허승호
Alternative Author(s)
Hur, Seung Ho
Journal Title
Journal of Cardiology
ISSN
1876-4738
Issued Date
2018
Keyword
Ventricular tachycardiaVentricular fibrillationMyocardial infarctionPrognosis
Abstract
Background:
Ventricular tachycardia or fibrillation (VT/VF) is a major cause of sudden cardiac death after acutemyocardial infarction (AMI). This study aims to investigate the clinical characteristics and outcomes of VT/VF, to identify the variables associated with VT/VF, and to construct a new scoring system.

Methods:
Patients with relatively preserved left ventricular ejection fraction (LVEF) ( 40%) included in the Korea Acute Myocardial Infarction Registry-National Institutes of Health registrywere enrolled in this study. Among 13,109 patients in the registry, a total of 10,334 (78.8%) had relatively preserved LVEF after AMI. Patients were divided into two groups based on whether they experienced life-threatening VT/VF during hospitalization or not. The predictors for VT/VF during hospitalizationwere assessed. In-hospital mortality and complications were recorded.

Results:
A total of 358 (3.5%) experienced life-threatening VT/VF. The VT/VF group was at an increased risk of in-hospital mortality (odds ratio 2.99) and cardiac death (odds ratio 3.40). Variables of diagnosis, Killip class, smoking, initial rhythm, left bundle branch block, and LVEF were significant indicators of VT/ VF. A new risk score system yielded acceptable discrimination function (c-statistics = 0.773).

Conclusions:
Relatively preserved LVEF patients could still be at risk of life-threatening VT/VF, which is related to a poor prognosis during the admission period. This new scoring system can be adopted to stratify the risk of VT/VF.
Department
Dept. of Internal Medicine (내과학)
Publisher
School of Medicine (의과대학)
Citation
Seung Hun Lee et al. (2018). A new risk score for ventricular tachyarrhythmia in acute myocardial infarction with preserved left ventricular ejection fraction. Journal of Cardiology, 72(5), 420–426. doi: 10.1016/j.jjcc.2018.04.008
Type
Article
ISSN
1876-4738
DOI
10.1016/j.jjcc.2018.04.008
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/41716
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Internal Medicine (내과학)
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