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Association between body mass index and 1-year outcome after acute myocardial infarction

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Affiliated Author(s)
김권배
Alternative Author(s)
Kim, Kwon Bae
Journal Title
PLoS One
ISSN
1932-6203
Issued Date
2019
Abstract
Objectives:
Beneficial effects of overweight and obesity on mortality after acute myocardial infarction (AMI) have been described as “Body Mass Index (BMI) paradox”. However, the effects of BMI is still on debate. We analyzed the association between BMI and 1-year clinical outcomes after AMI.

Methods:
Among 13,104 AMI patients registered in Korea Acute Myocardial Infarction Registry-National Institute of Health (KAMIR-NIH) between November 2011 and December 2015, 10,568 patients who eligible for this study were classified into 3 groups according to BMI (Group 1; < 22 kg/m2, 22 ≤ Group 2 < 26 kg/m2, Group 3; ≥ 26 kg/m2). The primary end point was all cause death at 1 year.

Results:
Over the median follow-up of 12 months, the event of primary end point occurred more frequently in the Group 1 patients than in the Group 3 patients (primary endpoint: adjusted hazard ratio [aHR], 1.537; 95% confidence interval [CI] 1.177 to 2.007, p = 0.002). Especially, cardiac death played a major role in this effect (aHR, 1.548; 95% confidence interval [CI] 1.128 to 2.124, p = 0.007).

Conclusions:
Higher BMI appeared to be good prognostic factor on 1-year all cause death after AMI. This result suggests that higher BMI or obesity might confer a protective advantage over the life-quality after AMI.
Department
Dept. of Internal Medicine (내과학)
Publisher
School of Medicine (의과대학)
Citation
Dae-Won Kim et al. (2019). Association between body mass index and 1-year outcome after acute myocardial infarction. PLoS One, 14(6), e0217525–e0217525. doi: 10.1371/journal.pone.0217525
Type
Article
ISSN
1932-6203
DOI
10.1371/journal.pone.0217525
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/42033
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Internal Medicine (내과학)
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