Long-term impact of dialysis-requiring AKI during the perioperative period of liver transplantation on postdischarge outcomes.
- Soojin Lee; Sehoon Park; Min Woo Kang; Hai‐Won Yoo; Kyungdo Han; Yaerim Kim; Jung Pyo Lee; Kwon Wook Joo; Chun Soo Lim; Yon Su Kim; Hyeongsu Kim; Dong Ki Kim
- Dept. of Internal Medicine (내과학)
- Issue Date
- Clinical Transplantation, Vol.33(8) : e13649-e13649, 2019
Patients undergoing liver transplantation (LT) are prone to dialysis‐re‐ quiring acute kidney injury (AKI‐D). However, long‐term prognoses among them need further investigation, as overall survival after LT is improving.
A nationwide, population‐based cohort study was conducted using the data of Korean National Health Insurance System between 2006 and 2015. The pa‐ tients who received dialysis during the perioperative period of LT were in the AKI‐D group, and the control group included those who did not undergo dialysis.
Among the 6879 patients who underwent LT, 968 were in the AKI‐D group. All‐cause mortality [adjusted hazard ratio (HR): 1.52 (1.26‐1.83), P < 0.001], end‐stage renal disease (ESRD) progression [adjusted HR: 2.93 (2.34‐3.66), P < 0.001], and ICU readmission [adjusted HR: 1.70 (1.44‐2.01), P < 0.001] within and after 90 days from discharge were increased in the AKI‐D group. When analyzed among those who recovered from dialysis at discharge, overall outcomes were similar to those of the AKI‐D group, except the long‐term mortality.
AKI‐D during the perioperative period of LT was associated with worse mortality, ESRD progression, and ICU readmission risk. The results of renal‐recov‐ered patients could indicate clinicians that achievement of dialysis independence is important to gain favorable long‐term postdischarge survival.
- acute kidney injury; liver transplantation
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- 1. Journal Papers (연구논문) > 1. School of Medicine (의과대학) > Dept. of Internal Medicine (내과학)
- Keimyung Author(s)
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