딸기코종형 주사로 오인된 원발 피부 소포중심 림프종 1예

Abstract

PCFCL is a subtype of primary cutaneous B-cell lymphoma (PCBCL), which is defined as a neoplasm of the centrocytes and centroblasts with or without the formation of follicles. It is rare in Asians and shows considerable variability in terms of clinical presentation and histological features, which makes it difficult to diagnose. A 77-year-old man visited our clinic with a 2-month history of erythematous telangiectatic patches and plaques on the face. Under the suspicion of phymatous rosacea, he received two pulsed dye-laser treatments at a local medical center and four pulsed dye-laser treatments at our outpatient clinic, but showed no improvement. Skin biopsy and immunohistochemical findings were compatible with PCFCL. Computed tomography (CT), positron emission tomography–computed tomography (PET-CT) and bone marrow biopsy revealed no evidence of extracutaneous involvement. Skin lesions improved after four cycles of chemotherapy with cyclophosphamide, vincristine, and prednisolone. Herein, we report an educational case of PCFCL misdiagnosed as phymatous rosacea.