다발성 골수종과 연관된 광범위 정상지질성 편평 황색종 1예

Other Titles
A Case of Diffuse Normolipemic Plane Xanthoma Associated with Multiple Myeloma
Authors
Won-Oh KimYoung-Wook RyooSung-Ae Kim
Department
Dept. of Dermatology (피부과학)
Issue Date
2019
Citation
대한피부과학회지, Vol.57(3) : 140-144, 2019
ISSN
0494-4739
Abstract
Diffuse plane xanthoma (DPX) presents with symmetric yellow-orange plaques primarily on the neck, upper trunk, flexural folds, and the periorbital region. Based on serum lipid and lipoprotein levels, these xanthomas are classified as normolipemic or hyperlipoproteinemic DPX. Diffuse normolipemic plane xanthoma (DNPX) is a rare condition that is not well studied yet. It is associated with reticulo-endothelial diseases, particularly multiple myeloma and monoclonal gammopathy of unknown significance (MGUS). A 62-year-old woman developed yellowish hyperpigmented papules and diffuse patches in the medial canthal area of her neck. Based on a skin biopsy and laboratory analyses, she was diagnosed with DNPX associated with multiple myeloma. This diagnosis demonstrates that dermatological lesions should be carefully assessed as they may be the first manifestation of an underlying hematological disease. We report herein a rare case of diffuse plane xanthoma associated with multiple myeloma and review the relevant literature.
Keywords
Diffuse plane xanthomaHematological diseaseMultiple myelomaNormolipemicXanthoma
URI
http://kumel.medlib.dsmc.or.kr/handle/2015.oak/42158
Appears in Collections:
1. Journal Papers (연구논문) > 1. School of Medicine (의과대학) > Dept. of Dermatology (피부과학)
Keimyung Author(s)
류영욱; 김성애
Full Text
https://koreamed.org/article/0048KJD/2019.57.3.140
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