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dc.contributor.authorDoo Sun Sim-
dc.contributor.authorMyung Ho Jeong-
dc.contributor.authorHyo Soo Kim-
dc.contributor.authorHyeon Cheol Gwon-
dc.contributor.authorKi Bae Seung-
dc.contributor.authorSeung Woon Rha-
dc.contributor.authorShung Chull Chae-
dc.contributor.authorChong Jin Kim-
dc.contributor.authorKwang Soo Cha-
dc.contributor.authorJong Seon Park-
dc.contributor.authorJung Han Yoon-
dc.contributor.authorJei Keon Chae-
dc.contributor.authorSeung Jae Joo-
dc.contributor.authorDong Ju Choi-
dc.contributor.authorSeung Ho Hur-
dc.contributor.authorIn Whan Seong-
dc.contributor.authorMyeong Chan Cho-
dc.contributor.authorDoo Il Kim-
dc.contributor.authorSeok Kyu Oh-
dc.contributor.authorTae Hoon Ahn-
dc.contributor.authorJin Yong Hwang-
dc.date.accessioned2020-05-04T16:30:26Z-
dc.date.available2020-05-04T16:30:26Z-
dc.date.issued2020-
dc.identifier.citationKorean Circulation Journal, Vol.50(2) : 120-129, 2020-
dc.identifier.issn1738-5555-
dc.identifier.otheroak-2020-0013-
dc.identifier.urihttp://kumel.medlib.dsmc.or.kr/handle/2015.oak/42553-
dc.description.abstractBackground and Objectives: There is a paucity of data regarding the benefit of clopidogrel monotherapy after dual antiplatelet therapy (DAPT) in patients treated with drug-eluting stents (DES). This study compared outcome between clopidogrel versus aspirin as monotherapy after DES for acute myocardial infarction (MI). Methods: From Korea Acute Myocardial Infarction Registry-National Institute of Health database, 1,819 patients treated with DES who were switched to monotherapy with clopidogrel (n=534) or aspirin (n=1,285) after uneventful 12-month DAPT were analyzed. The primary endpoint was net adverse clinical events (NACE), defined as a composite of death from any cause, MI, repeat percutaneous coronary intervention (PCI), stent thrombosis, ischemic stroke, or major bleeding during the period from 12 to 24 months. Results: After adjustment using inverse probability of treatment weighting, patients who received clopidogrel, compared with those treated with aspirin, had a similar incidence of NACE (0.7% and 0.7%; hazard ratio, 1.06; 95% confidence interval, 0.31–3.60; p=0.923). The 2 groups had similar rates of death from any cause (0.1% in each group, p=0.789), MI (0.3% and 0.1%, respectively; p=0.226), repeat PCI (0.1% and 0.3%, respectively; p=0.548), stent thrombosis (0.1% and 0%, respectively; p=0.121), major bleeding (0.2% in each group, p=0.974), and major adverse cardiovascular and cerebrovascular events (0.5% in each group, p=0.924). Conclusions: Monotherapy with clopidogrel, compared to aspirin, after DAPT showed similar clinical outcomes in patients with acute MI treated with DES.-
dc.description.statementofresponsibilityopen-
dc.publisherSchool of Medicine (의과대학)-
dc.rightsBY_NC_ND-
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/2.0/kr-
dc.subjectAntiplatelet agents-
dc.subjectDrug-eluting stents-
dc.subjectMyocardial infarction-
dc.titleClopidogrel versus Aspirin after Dual Antiplatelet Therapy in Acute Myocardial Infarction Patients Undergoing Drug-Eluting Stenting-
dc.typeArticle-
dc.contributor.localauthor허승호-
dc.contributor.alternativelocalauthorHur, Seung Ho-
dc.contributor.departmentDept. of Internal Medicine (내과학)-
dc.citation.volume50-
dc.citation.number2-
dc.citation.startpage120-
dc.citation.titleKorean Circulation Journal-
dc.citation.endpage129-
dc.identifier.doi10.4070/kcj.2019.0166-
dc.identifier.urlhttps://e-kcj.org/search.php?where=aview&id=10.4070/kcj.2019.0166&code=0054KCJ&vmode=FULL-


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