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The Effect of Severe Femoropopliteal Arterial Calcification on the Treatment Outcome of Femoropopliteal Intervention in Patients with Ischemic Tissue Loss

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Author(s)
박의준김형태노영남
Alternative Author(s)
Park, Ui JunKim, Hyoung TaeRoh, Young Nam
Publication Year
2020
Keyword
Ischemic tissue lossArterial calcificationEndovascular treatment
Abstract
Purpose:
We investigated the effect of severe calcification of the femoropopliteal artery on intervention outcomes in patients with ischemic tissue loss.

Materials and Methods:
A retrospective review of the first endovascular treatment of the femoropopliteal artery for ischemic tissue loss between May 2010 and February 2018 was performed. The calcification of femoropopliteal lesions was estimated by the Compliance 360° score, and lesions with a score of 4 were defined as severe calcification lesions.

Results:
Overall, 135 first femoropopliteal endovascular procedures on 135 limbs from 112 patients were included in this study. Among the 135 limbs that received treatement of the femoropopliteal arteries, 74 limbs had Trans-Atlantic Inter Society Consensus (TASC) A or B lesions and 61 limbs had TASC C or D lesions. Among 61 cases of TASC C or D lesions, 21 limbs (34.4%) had severe calcification; there was no statistically significant difference in limb salvage (P=0.75), and amputation-free survival (P=0.11) based on the degree of calcification. However, the survival rate in TASC C or D lesions was significantly different between the two groups (non-severe calcification group vs severe calcification group at 1-year, 2-years, and 3-years: 88.6%, 79.7%, and 61.0% vs 70.0%, 56.0%, and 28.0%, respectively, P=0.01). In multivariate analysis of influencing factors for poor survival in TASC C or D using the Cox proportional hazards model, severe calcification (hazard ratio, 2.362; 95% confidence interval, 1.035-5.391; P=0.01) was a statistically significant risk factor.

Conclusion:
Severe femoropopliteal artery calcification was associated with poor survival, especially in TASC C or D lesions.
Department
Dept. of Surgery (외과학)
Publisher
School of Medicine (의과대학)
Citation
Vascular Specialist International, Vol.36(2) : 96-104, 2020
Type
Article
ISSN
2288-7989
DOI
10.5758/vsi.200005
URI
http://kumel.medlib.dsmc.or.kr/handle/2015.oak/42774
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