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Tumor Size is Associated with Long-Term Outcomes after Resection of Gastric Gastrointestinal Stromal Tumors

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Author(s)
신경인이주엽이유진박경식
Alternative Author(s)
Lee, Ju YupLee, Yoo JinPark, Kyung Sik
Publication Year
2020
Keyword
Gastrointestinal stromal tumorsMitotic indexPrognosisRisk factorsStomach neoplasms
Abstract
The clinical outcomes after surgical resection of gastrointestinal stromal tumors (GISTs) vary widely due to the differences in tumor size and mitotic index. To analyze the long-term outcomes and prognosis of surgically resected gastric GISTs according to tumor size. We retrospectively analyzed the medical records of 269 patients who underwent surgery for GISTs at Keimyung University Dongsan Hospital from March 2000 to March 2017. We surveyed tumor size, mitotic index, recurrence after surgery, time to recurrence, treatment for recurrence, and mortality. The risk of recurrence of gastric GISTs was classified as very low, low, intermediate, and high risk according to the 2007 Journal of the national comprehensive cancer network (JNCCN). After excluding 69 patients who had simultaneous gastric adenocarcinoma, the outcomes of 200 patients were analyzed. Recurrence was observed in 7 patients: 1 in the very low risk group (1-2 cm), 2 in the very low risk group (less than 5 cm), and 3 in the high risk group. Death due to gastrointestinal bleeding occurred in 1 patient in the high risk group who had a tumor >10 cm. While the recurrence rates after surgical resection of GIST are very low, careful monitoring and regular follow-up are warranted, even for low risk patients.
Department
Dept. of Internal Medicine (내과학)
Citation
Kyung In Shin. (2020). Tumor Size is Associated with Long-Term Outcomes after Resection of Gastric Gastrointestinal Stromal Tumors. Keimyung Medical Journal, 39(1), 28-32. doi: 10.46308/kmj.2020.00073
Type
Jounral
DOI
10.46308/kmj.2020.00073
URI
http://kumel.medlib.dsmc.or.kr/handle/2015.oak/42803
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