계명대학교 의학도서관 Repository

Cerebral Small Vessel Disease and Alzheimer's Disease: A Review

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Affiliated Author(s)
김해원홍정호전재천
Alternative Author(s)
Kim, Hae WonHong, Jeong HoJeon, Jae Cheon
Journal Title
Frontiers in Neurology
ISSN
1664-2295
Issued Date
2020
Keyword
Alzheimer's diseasePETcerebral small vessel diseasedementiawhite matter hyperintensity
Abstract
Alzheimer's disease (AD) is the most common cause of dementia. Despite this, clear pathophysiology for AD has not been confirmed, and effective treatments are still not available. As AD results in a complex disease process for cognitive decline, various theories have been suggested as the cause of AD. Recently, cerebral small vessel disease (SVD) has been suggested to contribute to the pathogenesis of AD, as well as contributing to vascular dementia. Cerebral SVD refers to a varied group of diseases that affect cerebral small arteries and microvessels. These can be seen as white matter hyperintensities, cerebral microbleeds, and lacunes on magnetic resonance imaging. Data from epidemiological and clinical-pathological studies have found evidence of the relationship between cerebral SVD and AD. This review aims to discuss the complex relationship between cerebral SVD and AD. Recent reports that evaluate the association between these diseases will be reviewed.
Department
Dept. of Nuclear Medicine (핵의학)
Dept. of Neurology (신경과학)
Dept. of Emergency Medicine (응급의학)
Publisher
School of Medicine (의과대학)
Citation
Hae Won Kim et al. (2020). Cerebral Small Vessel Disease and Alzheimer’s Disease: A Review. Frontiers in Neurology, 11, 927. doi: 10.3389/fneur.2020.00927
Type
Article
ISSN
1664-2295
DOI
10.3389/fneur.2020.00927
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/43080
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Emergency Medicine (응급의학)
1. School of Medicine (의과대학) > Dept. of Neurology (신경과학)
1. School of Medicine (의과대학) > Dept. of Nuclear Medicine (핵의학)
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