유기 인산염 중독의 영구 신경학적 후유증으로서의 미만성 소뇌 기능 장애: 증례 보고

Abstract

The diffuse cerebellar dysfunction as a permanent neurological sequela of or-ganophosphate poisoning has not yet been reported in the published literature. We report a diffuse cerebellar dysfunction as a permanent manifestation of or-ganophosphate poisoning. A 55-year-old man diagnosed with acute organophos-phate poisoning was brought to the emergency room of our hospital. He had slurred, monotonous scanning speech with irregularly distributed articulatory deficits, and prominent bilateral limb ataxia. He presented left-beating spontaneous nystagmus with a downbeat component and strong downbeating nystagmus after head shaking. He also showed saccadic hypometria with a normal saccadic velocity at fixed horizontal saccades and symmetrically impaired horizontal smooth pursuit on both sides. The poisoning of organophosphate poisoning may lead to a diffuse permanent cerebellar dysfunction as a neurological sequela event.