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Comparison of the Characteristics of Asymptomatic and Presymptomatic Patients with Coronavirus Disease 2019 in the Republic of Korea

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Affiliated Author(s)
현미리이지연박재석김진영김현아
Alternative Author(s)
Hyun, Mi RiLee, Ji YeonPark, Jae SeokKim, Jin YoungKim, Hyun Ah
Journal Title
J Epidemiol Glob Health
ISSN
2210-6014
Issued Date
2021
Keyword
AsymptomaticChest radiographCoronavirus disease 2019C-reactive proteinPneumoniaSevere acute respiratory syndrome coronavirus 2
Abstract
Purpose:
This retrospective study aimed to evaluate the baseline characteristics of asymptomatic patients with coronavirus disease 2019 at admission and to follow-up their clinical manifestations and radiological findings during hospitalization.

Methods:
Patients with coronavirus disease 2019 who were asymptomatic at admission were divided into two groups—those with no symptoms until discharge (group A) and those who developed symptoms after admission (group B). Patients who could not express their own symptoms were excluded.

Results:
Overall, 127 patients were enrolled in the study, of whom 19 and 108 were assigned to groups A and B, respectively. The mean age and median C-reactive protein level were higher in group B than in group A. All patients in group A and one-third of patients in group B had normal initial chest radiographs; 15.8% and 48.1% of patients in groups A and B, respectively, had pneumonia during hospitalization. One patient in group B, whose condition was not severe at the time of admission, deteriorated due to aggravated pneumonia and was transferred to a tertiary hospital.

Conclusion:
We summarize the clinical characteristics during hospitalization of patients with coronavirus disease 2019 who were purely asymptomatic at the time of admission. The majority of asymptomatic patients with coronavirus disease 2019 were discharged without significant events during hospitalization. However, it may be difficult to predict subsequent events from initial chest radiographs or oxygen saturation at admission.
Department
Dept. of Internal Medicine (내과학)
Dept. of Radiology (영상의학)
Publisher
School of Medicine (의과대학)
Citation
Miri Hyun et al. (2021). Comparison of the Characteristics of Asymptomatic and Presymptomatic Patients with Coronavirus Disease 2019 in the Republic of Korea. J Epidemiol Glob Health, 11, 354–363. doi: 10.1007/s44197-021-00011-7
Type
Article
ISSN
2210-6014
DOI
10.1007/s44197-021-00011-7
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/44128
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Internal Medicine (내과학)
1. School of Medicine (의과대학) > Dept. of Radiology (영상의학)
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