Leg paralysis after AstraZeneca COVID-19 vaccination diagnosed as neuralgic amyotrophy of the lumbosacral plexus: a case report
- Affiliated Author(s)
- 석흥열; 이재혁; 조장혁
- Alternative Author(s)
- Seok, Hung Youl; Yi, Jae Hyuck; Cho, Jang Hyuk
- Journal Title
- J Int Med Res
- ISSN
- 1473-2300
- Issued Date
- 2021
- Keyword
- Coronavirus disease 2019; vaccination; lumbosacral plexus; paralysis; case report; complication
- Abstract
- The ongoing global administration of vaccines for coronavirus disease 2019 (COVID-19) means that increasing numbers of patients are likely to present with post-vaccination complications. We describe the first reported case of neuralgic amyotrophy (NA) involving the lumbosacral plexus occurring after AstraZeneca COVID-19 vaccination. The patient presented with acute-onset leg paralysis following administration of the vaccine. Based on the clinical, electrodiagnostic, and radiologic findings, the patient was diagnosed with post-vaccination NA. We speculate that the COVID-19 vaccine elicited an immune-mediated inflammatory response to the injected antigen due to inflammatory immunity in a patient with predisposed susceptibility to NA.
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