Early Detection of Secondary Bladder Urothelial Carcinoma and Disseminated Bone Metastases with Normal Prostate-Specific Antigen Level after Pelvic Salvage Radiotherapy in Prostate Cancer
- Affiliated Author(s)
- 신택준; 김병훈; 변상준
- Alternative Author(s)
- Shin, Teak Jun; Kim, Byung Hoon; Byun, Sang Jun
- Journal Title
- Life (Basel)
- ISSN
- 2075-1729
- Issued Date
- 2023
- Keyword
- bone metastases; normal prostate-specific antigen; pelvic radiotherapy; prostate cancer; secondary bladder cancer
- Abstract
- This report describes the case of a 65-year-old man who presented with gross hematuria and a history of pelvic salvage radiotherapy for prostate cancer. Cystoscopy and transurethral resection of the bladder revealed urothelial carcinoma. Subsequently, disseminated bone metastases were detected with normal prostate-specific antigen (PSA) levels, and palliative radiotherapy and systemic chemotherapy were administered. Because gross hematuria can appear in both acute/chronic cystitis and bladder cancer in patients who have undergone pelvic radiotherapy for prostate cancer, close follow-up along with a detailed evaluation is needed. In addition, because prostate cancer disease progression with normal PSA levels may be associated with specific pathological findings, a detailed evaluation of symptoms and a careful review of pathologic reports are important.
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