https://kumel.medlib.dsmc.or.kr/handle/2015.oak/850 2026-04-04T17:36:56Z 2026-04-04T17:36:56Z 이현아 이형 https://kumel.medlib.dsmc.or.kr/handle/2015.oak/15935 2023-01-26T18:12:01Z 2010-12-31T15:00:00Z

Title: 심방세동 환자에서 신장경색과 동시에 발병한 뇌경색 Author(s): 이현아; 이형 Abstract: Although renal infarction causes irreversible ischemic damage, it is difficult to be detected due to rare occurrence and non-specific clinical manifestations. A 73-year-old woman with atrial fibrillation presented with simultaneously developed right hemiparesis and right flank pain lasting 3.5 hours. Brain magnetic resonance imaging revealed left cerebral infarction suggesting embolic causes and we started intravenous anti-coagulation with heparin. We performed abdominal computed tomography to know the cause of persistent flank pain, and the patient was diagnosed as having acute renal infarction. Clinicians should be aware of the possibility of co-occurrence of the cerebral and renal infarctions, especially when patients had acute flank pain in addition to neurological signs or symptoms.

2010-12-31T15:00:00Z 이현아 https://kumel.medlib.dsmc.or.kr/handle/2015.oak/15934 2023-01-26T18:12:01Z 2010-12-31T15:00:00Z

Title: 인지기능장애가 동반된 비타민 E 결핍증후군 Author(s): 이현아 Abstract: Vitamin E deficiency syndrome, which is related to cystic fibrosis, abetalipoproteinemia, hepatobiliary abnormalities, short bowel syndrome and idiopathic causes, can have a profound effect on the nervous system. Besides hyporeflexia, ataxia, extraocular muscular disturbances, muscle weakness or blurred vision, cognitive dysfunction associated with vitamin E deficiency can be seen. A 25-year-old male presented with progressive ataxia and cognitive dysfunction for 6 months. He showed also muscular weakness, proprioceptive dysfunction on the neurological examination. Brain and spinal MRI, brain SPECT, CSF evaluation were normal. Serum vitamin E level was lower than normative value. By vitamin E supplement, muscular weakness, cognitive dysfunction were a little bit improved. We couldn’t find any causative abnormalities for vitamin E deficiency. We experienced a case of isolated vitamin E deficiency syndrome with cognitive

2010-12-31T15:00:00Z 김연수 김지훈 김도형 조용원 https://kumel.medlib.dsmc.or.kr/handle/2015.oak/15933 2023-01-26T18:12:00Z 2010-12-31T15:00:00Z

Title: 라모트리진에 의해 유발된 백질뇌병증 Author(s): 김연수; 김지훈; 김도형; 조용원 Abstract: Lamotrigine (LTG) is a broad-spectrum antiepileptic drug and is well tolerated. Hypersensitivity reactions are well known serious adverse effects that may occur in some patients, including skin rashes, aseptic meningitis and leukopenia. However, there have been no reported cases of diffuse encephalopathy due to LTG in Korea. We report a case of encephalopathy which may have been caused by LTG. A 61-year-old male presented with complex partial seizures which may have been due to a transient ischemic attack. His brain MRI was normal at that time. His seizure was controlled with oxcarbazepine 600 mg. Ten days later, we switched it to LTG. After 3 days on LTG, he showed cognitive symptoms as general malaise, decrease of verbal fluency, inappropriate words, and slowness of thought. His follow-up MRI showed diffuse abnormal signals in the bilateral white matter in the FLAIR image and decreased signals in the ADC map. After we changed LTG to oxcarbazepine, his mental functions slowly improved. At 9 days after stopping LTG, his follow up MRI showed decreased abnormal signals in the bilateral white matter of the FLAIR image. His clinical symptoms and MRI findings continuously improved without any specific treatments. Our patient presented diffuse encephalopathy after starting LTG and improved the symptoms after stopping LTG. Though the cause of diffuse leukoencephalopathy was not confirmed, we strongly suspected that LTG was related with his brain lesion by temporal relation. We consider it is one of the possible causes if some patient using LTG develops diffuse leukoencephalopathy.

2010-12-31T15:00:00Z 윤성도 https://kumel.medlib.dsmc.or.kr/handle/2015.oak/15929 2023-01-26T18:11:42Z 2010-12-31T15:00:00Z

Title: 양수의 기능 Author(s): 윤성도 Abstract: Adequate amniotic fluid volume is necessary for proper fetal growth and development. However, abnormalities of amniotic fluid volume are frequently associated with fetal disease, maternal disease, or both. Thus, an understanding of amniotic fluid dynamics and the efficacy and limitations of the various methods of estimating amniotic fluid volume can improve management and perinatal outcomes. Compared with the era in obstetric practice before the advent of ultrasonography, much is presently known about the normative values for amniotic fluid volume and the mechanisms by which this important fluid is regulated. Future research should focus on achieving a better understanding of these issues so fundamentally related to the maintenance of maternal-fetal homeostasis.

2010-12-31T15:00:00Z