임신중독증에서 간기능검사 이상에 관한 연구

Other Titles
Abnormal Liver Function Test in Toxemia
Authors
강영우박승국
Department
Dept. of Internal Medicine (내과학)
Issue Date
1988
Citation
Keimyung Medical Journal, Vol.7(1) : 128-135, 1988
Abstract
Toxemia is the first one of three main causes of maternal mortality in Korea, but the pathogenesis is uncertain. Toxemia involves multiple organs and mianifests various clinical symptoms including abnormal liver function test. Although it is transient and disappears after delivery, the clinician always should be aware of it. We analyzed 997 cases of toxemia in 19537 obstetric charts of pregnant women admitted in the department of obstetrics & gynecology, Dongsan medical Center in a period of ten years from January 1977 to December 1986. The result were as follows: 1) The incidences of abnormal liver profile in toxemia were 5.4% of bilirubin, 82.9% cholesterol, 56.6% total protein, 86.4% albumin, 13.9% globulin, 91.9% ALP, 23.3% AST, and 9.4% ALT. 2) Satistical significance between abnormal liver profile and gestational age was observed in total protein, albumin, ALP, and AST(p<0.005). 3) Toxemia compared with abnormal liver profile of nontoxemia group showed statistical significance in all items of liver profile(p<0.005). In conclusion, toxemia result in abnormal liver function test, especially abnormal total protein and AST value in abnormal gestational age.
URI
http://kumel.medlib.dsmc.or.kr/handle/2015.oak/14523
Appears in Collections:
1. Journal Papers (연구논문) > 1. School of Medicine (의과대학) > Dept. of Internal Medicine (내과학)
2. Keimyung Medical Journal (계명의대 학술지) > 1988
Keimyung Author(s)
강영우; 박승국
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