자궁 평활근종의 치료에 D-Trp⁶-Luteinizing Hormone Releasing Hormone의 사용과 효과에 관한 1례 보고

Other Titles
A Case report of uterine leiomyoma treated with D-Trp⁶-Luteinizing hormone releasing hormone
Authors
이두룡이정호이형종이상숙
Department
Dept. of Obstetrics & Gynecology (산부인과학); Dept. of Pathology (병리학)
Issue Date
1989
Citation
Keimyung Medical Journal, Vol.8(1) : 167-172, 1989
Abstract
The 24 years old menstruous female having one huge uterine leiomyoma was treated with D-Trp⁶-LHRH. D-Trp⁶-LHRH is superactive agonist of LHRH and suppresses the secretion of gonadal steroids, so it can reduce the estrogen dependant myoma size remarkably. There were many case reports fo the good clinical effect of D-Trp⁶-LHRH. But the size of uterine myoma in this patient did not reduce remarkably after the total 6th injection of D-Trp⁶-LHRH, and uterine myomectomy was performed one month later after the last injection. The light microscopic finding of resected leiomyoma showed diffuse marked hyaline degeneration throughout the entire myoma mass. These findings suggest that this tumor is hormonally inactive due to the insufficient estrogen receptor via hyaline degeneration of myoma mass, so do not respond to suppressed estrogen level.
URI
http://kumel.medlib.dsmc.or.kr/handle/2015.oak/14574
Appears in Collections:
1. Journal Papers (연구논문) > 1. School of Medicine (의과대학) > Dept. of Obstetrics & Gynecology (산부인과학)
1. Journal Papers (연구논문) > 1. School of Medicine (의과대학) > Dept. of Pathology (병리학)
2. Keimyung Medical Journal (계명의대 학술지) > 1989
Keimyung Author(s)
이두룡; 이정호; 이형종; 이상숙
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