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자궁 평활근종의 치료에 D-Trp⁶-Luteinizing Hormone Releasing Hormone의 사용과 효과에 관한 1례 보고

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Author(s)
이두룡이정호이형종이상숙
Keimyung Author(s)
Lee, Du RyongRhee, Jeong HoLee, Hyeong JongLee, Sang Sook
Department
Dept. of Obstetrics & Gynecology (산부인과학)
Dept. of Pathology (병리학)
Journal Title
Keimyung Medical Journal
Issued Date
1989
Volume
8
Issue
1
Abstract
The 24 years old menstruous female having one huge uterine leiomyoma was treated with D-Trp⁶-LHRH. D-Trp⁶-LHRH is superactive agonist of LHRH and suppresses the secretion of gonadal steroids, so it can reduce the estrogen dependant myoma size remarkably. There were many case reports fo the good clinical effect of D-Trp⁶-LHRH. But the size of uterine myoma in this patient did not reduce remarkably after the total 6th injection of D-Trp⁶-LHRH, and uterine myomectomy was performed one month later after the last injection. The light microscopic finding of resected leiomyoma showed diffuse marked hyaline degeneration throughout the entire myoma mass. These findings suggest that this tumor is hormonally inactive due to the insufficient estrogen receptor via hyaline degeneration of myoma mass, so do not respond to suppressed estrogen level.
Alternative Title
A Case report of uterine leiomyoma treated with D-Trp⁶-Luteinizing hormone releasing hormone
Keimyung Author(s)(Kor)
이두룡
이정호
이형종
이상숙
Publisher
Keimyung University School of Medicine
Citation
이두룡 et al. (1989). 자궁 평활근종의 치료에 D-Trp⁶-Luteinizing Hormone Releasing Hormone의 사용과 효과에 관한 1례 보고. Keimyung Medical Journal, 8(1), 167–172.
Type
Article
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/14574
Appears in Collections:
2. Keimyung Medical Journal (계명의대 학술지) > 1989
1. School of Medicine (의과대학) > Dept. of Obstetrics & Gynecology (산부인과학)
1. School of Medicine (의과대학) > Dept. of Pathology (병리학)
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