계명대학교 의학도서관 Repository

Platelets apheresis 수혈에 의한 혈소판 회복율

Metadata Downloads
Author(s)
전동석
Alternative Author(s)
Jeon, Dong Seok
Publication Year
1990
Abstract
To determine the reative importance of clinical factors on the efficacy of platelet transfusion, 37 random multipie-donor platelet concentrate transfusions and 91 random platelets apheresis transfusions were studied. One-hour and twenty four-hour corrected count increment(CCI) as efficacy of platelet transfusion were measured. Disease groups included acute lymphocytic leukemia, acute nonlympocytic leukemia, aplastic anemia, immune thrombocytopenic purpua, malignant tumor and others(panperitonitis, burn gall stone, liver cirrhosis and iron deficiency anemia). All disease groups except aplastic anemia group comparing with others group, showed significantly decreased efficacy of platelets apheresis transfusion, however there was no statistical singificance between disease groups. Patients with fever and/or splenomegaly showed significantly decreased efficacy of platelets apheresis transfusion. Patients with repeated platelet transfusion compared to patients without transfusion, showed decreased efficacy of platelet transfusion with statistica significance in fourth transfusions. In donors, after plateletpheresis using blood-cell separator(Haemonetics V50), hemoglobin level, WBC count, and platelet count were decreased 10.6%, 4.2%, and 31% respectively. And total platelet count in a platelets apheresis was approximately ten times more than in a platelet concentrate, however contaminating white blood cell count in platelets apheresis was signficantly higher than in platelet concentrate. The frequency of the refractoriness to multiple-donor platelet concentrate transfusions was higher than platelets apheresis transfusion. The findings of this study suggest that understanding the factors affecting the efficacy of platelet transfusion and the use of latelets apheresis are necessary to decrease refractoriness to platelet transfusion.
Alternative Title
Efficacy of Platelets Apheresis Transfusion
Department
Dept. of Laboratory Medicine (진단검사의학)
Publisher
Keimyung University School of Medicine
Citation
Keimyung Medical Journal, Vol.9(1) : 23-34, 1990
Type
Article
URI
http://kumel.medlib.dsmc.or.kr/handle/2015.oak/14606
Authorize & License
  • AuthorizeOpen
Files in This Item:

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.