임상가검물에서 분리된 Gram음성 간균의 항균제감수성

Other Titles
Antimicrobial Drug Susceptibility of Gram Negative Bacilli Isolated from Clinical Specimens
Authors
백원기서성일서민호
Department
Dept. of Microbiology (미생물학)
Issue Date
1990
Citation
Keimyung Medical Journal, Vol.9(4) : 409-417, 1990
Abstract
One hundred and one Gram negative bacilli isolated from various clinical specimens were tested for antimicrobial susceptibility to 21 drugs including quinolones. P. aeruginosa(35 strains) was most frequently isolated and followed by Proteus(27),E. coli(20), Klebsiella(16), Citrobacter(2), Serratia(1) in the decreasing order. The majority of strains isolated except P. aeruginosa were very susceptible to quinolone antibiotics tested. In P. aeruginosa all strains were resistant to nalidixic acid, and 11.4-17.1% to enoxacin, norfloxacin(NF), and ciprofloxacin. The other species had no resistant strains to Nf, and especially E. coli was very highly susceptible to all quinolone antibiotics tested. 90%MICs of quinolones against P. aeruginosa were 32->64 and the other species was <0.25-16. Resistance frequency of P. aeruginosa to beta-lactam antibiotics were 42.9-60% and 90% MICs of these drugs were also high. To amikacin, 51.4% of P. aeruginosa was resistant, but all strains of the other species were susceptible except one strain. The majority of isolated strains were susceptible to chloramphenicol, tetracycline, sulfisomidine, and trimethoprim. Organisms multiply resistant to drugs were noted in almost all isolates tested. The strain numbers of multiply resistant to 6 or more drugs were 16 strains of E. coli, 24 strains of P. aeruginosa, 16 strains of Proteus, 3 strains of Klebsiella.
Keywords
Gram negative bacilliQuinolone resistance
URI
http://kumel.medlib.dsmc.or.kr/handle/2015.oak/14653
Appears in Collections:
1. Journal Papers (연구논문) > 1. School of Medicine (의과대학) > Dept. of Microbiology (미생물학)
2. Keimyung Medical Journal (계명의대 학술지) > 1990
Keimyung Author(s)
백원기; 서성일; 서민호
File in this Item
9-409.pdf(407.74 kB)Download
Export
RIS (EndNote)
XLS (Excel)
XML


qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

BROWSE